barbiturate
barbiturate
Definition
bar·bi·tu·rate (bär bic̸h′ər it, -ə rāt′; bär′bə tyo̵or′it, -to̵or′-, -āt′; often, -bic̸h′ə wit)
noun
any depressant drug, as phenobarbital, derived from barbituric acid and used as a sedative, sleeping pill, anticonvulsant, etc.
Etymology: barbituric acid + -ate
barbiturate
Usage Examples
Converse of object
- include: The animal experimentation involved in Cold Buster's development included rats being frozen, starved, and injected with drugs, including barbiturates.
- use: SCULLY: Well, I'd use a fast-acting barbiturate like pentobarbital.
- take: Q. My mother aged 71 has recently been taking barbiturate sleeping pills.
- receive: Withdrawal symptoms occur in infants born to women who receive barbiturates during the last trimester of pregnancy.
- ingest: Death commonly occurs after 2 to 10g of ingested barbiturate.
- administer: Valium® ) if indicated, at a dose of 1-2 mg/kg iv ( do not administer barbiturates or other cardiorespiratory depressants ).
Converse of subject
- induce: Anesthesia can be induced by barbiturate or non-barbiturate drugs.
Adjective modifier
- other: It has stronger anticonvulsant properties than most other barbiturates, and may be preferentially concentrated in metabolically active epileptic foci.
- most: In general, an oral dose of 1g of most barbiturates produces serious poisoning in an adult.
Modifies a noun
- intoxication: And there was barbiturate intoxication and deaths from Vioxx which I found so helpful.
- anesthesia: Indeed, there is evidence to suggest that given with barbiturate anesthesia, it can reduce the relapse rate with anesthetic withdrawal.
- poisoning: She died at the age of 53 from barbiturate poisoning; attributed to suicide.
- drug: Phenobarbital and other barbiturate drugs and anti-anxiety drugs like Valium exert their calming effects by enhancing the activity of GABA-A receptors.
- overdose: The Dutch use a barbiturate overdose, often combined with curare, to cause death, which results from not breathing, by asphyxia.
- tablet: Barbiturate sleeping tablets are notorious for causing dreadful nightmares, and even hallucinations, in elderly folk.
Preposition: during
- trimester: Withdrawal symptoms occur in infants born to women who receive barbiturates during the last trimester of pregnancy.
Preposition: with
- excitement: Elderly or debilitated patients may react to barbiturates with marked excitement, depression or confusion ( see ' Contra-indications ' ).
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